Create Spritesheets
Spritehandler can also be used for simple sprite packing using either on-disk images or packing automatically from render output.

Particles, Static and Animated
Using the Spritehandler node group with particle systems greatly expand what is possible with Blender’s limited particle rendering tools.

Material Variation with Atlases
By driving the node groups index function with object data or randomization, Spritehandler can be used to create complex material variations across instances.

Atlas to Mesh
Convert atlas maps to mesh objects based on their grid layout and alpha channels.

Playback of Spritesheets and Flipbooks
:warning: Eevee warning: Due to a bug/limitation in Eevee, spritesheet indexing can occasionally show the wrong frame. The issue specifically when using the spritesheet node group and does not affect creating spritesheets. At time of writing I'm experimenting with a workaround but can make no promises as the bug is part of Blender.:

Spritehandler’s enables the use of sprite sheets within material nodes. Creation of sprite planes through the operator will setup a time node, removing the need to keyframe playback.